oncogene

英 ['ɒŋkə(ʊ)dʒiːn] 美['ɑŋkə,dʒin]
  • n. [遗][肿瘤] 致癌基因

英英释意


1. a gene that causes normal cells to change into cancerous tumor cells

英文词源


oncogene (n.)
1969, from onco- + -gene, from root of Greek gignere (perf. genui) "beget," from PIE *gen- "produce" (see genus). Related: Oncogenesis (1832).

实用场景例句


A normal gene that has the potential to become an oncogene.
原致肿瘤基因一种有可能成为肿瘤基因的正常基因.

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Oncogene: Gene that can cause cancer.
致癌基因: 能够导致恶性肿瘤的基因.

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Objective : To approach the relationship between oncogene C - fos , K - ras and intrahep atic cholangiocarcinoma ( ICC ) and the significance.
目的: 探讨癌基因产物C -fos 、 K -ras 蛋白与肝内胆管癌发生的关系及其生物学意义.

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The stem cell leukemia ( SCL ) gene is a new oncogene related with leukemogenesis.
干细胞白血病 ( CL ) 因是新发现的与白血病发生有关的癌基因.

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Conclusion Mutation of RET proto - oncogene might play an role in the familial Hirschsprung � � s disease.
结论RET基因突变与家族性先天性巨结肠症的发生有关.

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The proto - oncogene c - fos mRNA expression was assessed using reverse transcription polymerase chain reaction ( RT - PCR ).
用逆转录聚合酶链式反应 ( RT -PCR ) 检测心肌细胞原癌基因c-fosmRNA的表达.

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Objective : To confirm the cleavage activity of ribozyme Rz 199 to oncogene K ras messenger RNA.
目的: 确定人工设计的核酶Rz199对原癌基因K-rasmRNA的体外切割活性,为K-ras特异性核酶的体内应用提供依据.

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Moreover, transformation of tumor cells is involved in oncogene amplification or promoter enhancement.
而且, 肿瘤细胞的转型通常涉及致癌基因的扩大,以及启动子的加强.

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The biological characteristic of carcinomas is determined both by the stromal microenvironment and the oncogene anti - oncogene.
肿瘤的生物学特性不仅是由癌基因和抑癌基因来调控的,还依赖于由其间质等构成的微环境.

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Figure 1 . The difference between an oncogene in a virus and in a cell.
图1细胞癌基因和病毒原癌基因的不同.

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P 53 is an important proto - oncogene involved in the regulation of cell - cycle and apoptosis.
P53蛋白是参与调节细胞周期和凋亡过程的原癌基因.

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The proto - oncogene c - fos mRNA expression was assessed using reverse transcription polymerase chain reaction ( RT - PCR ).
用逆转录聚合酶链式反应 ( RT -PCR ) 检测心肌细胞原癌基因c-fosmRNA的表达.

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Oncogene products are links in signal chains that stretch from the cell surface to cell nucleus.
图2.原癌基因的产物与细胞表面到细胞核的信号传递链有关.

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